Job Details
Senior Clinical Data Manager
- £Competitive
 - Durham, North Carolina, United States
 - Permanent
 
Join a Global Leader in Clinical Research
Are you a seasoned Clinical Data Manager with a passion for driving high-quality data outcomes across global clinical trials? We are looking for a Senior Clinical Data Manager to join a world-leading CRO and to lead the charge on complex, multi-regional studies and to serve as a trusted partner with a dedicated client.
This is a high-impact role ideal for a data management expert ready to take ownership of global study delivery, influence cross-functional strategies, and mentor the next generation of data professionals.
Key Responsibilities
- Act as the primary point of contact for clients on all data management deliverables across assigned studies or programs.
 - Lead and manage multiple large global studies or an integrated program of studies, ensuring timely and quality-driven delivery.
 - Negotiate directly with customers on timelines, budgets, resources, and processes, building strong long-term partnerships.
 - Provide leadership and mentorship to junior team members, offering ongoing training, oversight, and professional development support.
 - Oversee all aspects of data management activities, including data cleaning, database design, CRF development, and database lock.
 - Collaborate cross-functionally with internal stakeholders including biostatistics, clinical operations, and project management teams.
 - Ensure compliance with regulatory standards (GCP, ICH, CDISC) and company SOPs.
 
What We’re Looking For
- Minimum of 10 years' relevant experience in clinical data management within a CRO, pharma, or biotech setting.
 - At least 7 years as an independent Lead Data Manager, with full responsibility for study-level DM deliverables.
 - Proven track record managing large-scale global clinical trials.
 - Demonstrated experience in client-facing roles and direct negotiations.
 - Strong leadership skills with a passion for team development and knowledge-sharing.
 - Expertise in industry-standard EDC systems and familiarity with CDISC/CDASH standards.
 - Exceptional communication, organizational, and problem-solving skills.
 
Why Join Us?
- Be part of a global, mission-driven team at the forefront of clinical innovation.
 - Work on diverse, complex studies with top-tier sponsors and collaborators.
 - Opportunities for career growth, leadership, and global mobility.
 - Supportive, flexible work culture that values excellence, accountability, and collaboration.
 
Ready to advance your data management career?
Apply now and become part of a global organisation that’s shaping the future of clinical research.